According to the 2013 AHA/ACC Lifestyle Management Guidelines, adults (>21 years of age) are recommended to use a high dose statin (daily dose lowers LDL0C by approximately >50%) if any of the following criteria are met:
- Clinical ASCVD*
- LDL-C ≥190 mg/dL**
- Diabetic, age 40-75 years old, with an LDL-C of 70-189 mg/dL, and an estimated ASCVD risk of ≥7.5%
- Non-diabetic, age 40-75 years old, with and LDL-C of 70-189, with an estimated ASCVD risk of ≥7.5%
*Clinical ASCVD includes acute coronary syndrome, or a history of myocardial infarction, stable or unstable angina, coronary or other arterial revascularization, stroke, transient ischemic attack, or peripheral arterial disease presumed to be of atherosclerotic origin.
** Consider LDL-C-lowering non-statin therapy to further reduce LDL-C
According to the 2013 AHA/ACC Lifestyle Management Guidelines, adults (>21 years of age) are recommended to use a moderate dose statin (daily dose lowers LDL0C by approximately 30% to <50%) if any of the following criteria are met:
- Age >75 OR if not candidate for high-intensity statin
- Diabetic, age 40-75 years old, with an LDL-C of 70-189 mg/dL, and an estimated ASCVD risk of <7.5%
- Non-diabetic, age 40-75 years old with and LDL-C of 70-189 mg/dL and an estimated ASCVD risk of 5% to <7.5%