Long-Term Dual Anti-platelet Therapy After Stent Placement

What is it?

Aspirin 75-100 mg

+ P2Y12 receptor blocker (clopidogrel 75 mg daily; or prasugrel 10 mg daily, unless < 60 kg → 5 mg daily; or ticagrelor 90 mg twice daily).

Purpose: reduce the risk of stent thrombosis, which can lead to heart attack or death.

How long do you need to take it?

The optimal amount of time for antiplatelet therapy is unknown. However, 12 months is the standard duration for stable patients. After 12 months, only aspirin is continued for an indefinite period of time.

What is the minimum amount of time I should take antiplatelets?

4 weeks for bare metal stents

6 months for drug-eluting stents


Cutlip, D. (2014, August 4). Antiplatelet therapy after coronary artery stenting. UpToDate. Retrieved from

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