Calcium Channel Blockers medications are to used to treat Angina, Arrhythmia, Hypertension. By blocking the L-Type Calcium Channels on vascular smooth muscle, cardiac muscle, cardiac nodal tissue, the medications will decrease the work-load on the heart. This effect will allow the heart to relax and work more effectively. Dihydropyridine can be used as antiarrhythmic. Dihydropyridines act mostly on cardiac tissues, whereas 3 generations of Dihydropyridines are classified based on the ability to affect on the cardiac muscle. The side effects of the L-Type Calcium Channels are ranging from peripheral edema to dizziness, Headache. Contraindications to Calcium Channel Blockers are worth noting such as hypotention, heart block, Wolff-Parkinson-White syndrome, etc.